While true allergies to local anesthetics can occur, they are extremely rare despite numerous large studies of people who experienced adverse reactions after using these medications. Skin testing revealed that nearly all of these people showed no evidence of allergy to local anesthetics and were able to tolerate injections with these medications. Most allergists skin test with preservative-free (methylparaben-free), epinephrine-free local anesthetics. If skin testing is negative, then subcutaneous... read more
